Clinical Trials and Studies

Do you have heart failure and live near Massachusetts General Hospital in Boston, Massachusetts? Researchers are testing whether an online program helps lower the number of times patients with heart failure return to the hospital. You may be able to participate if you are at least 18 years old, have heart failure, and live within 30 miles of Massachusetts General Hospital in Boston.

Are you a parent of a child in kindergarten to 5th grade? Or do you lead teachers who teach children in these grades? Researchers are testing if active learning can get children to move more. Active learning blends physical activity into school lessons. The study is taking place in Houston, Texas.

Do you do shift work and are interested in metabolic health? This study looks at how diet may affect circadian misalignment. To join, you must be 18 to 45 years old and in good health. As a participant, you will stay in the study hospital twice and get all your meals during the study. The study is taking place at Brigham and Women's Hospital in Boston, Massachusetts.

Does your child have sleep apnea? Researchers are testing whether a device to help improve airflow in the upper airway can help people with sleep apnea. Participants must be between 3 and 21 years old and have obstructive sleep apnea. The study is taking place in Ann Arbor, Michigan.

Do you have sickle cell disease? Researchers are testing whether a drug that is often used to treat nausea caused by chemotherapy can also treat chronic pain and improve quality of life in adults living with sickle cell disease. Participants must be between 18 and 80 years old. The study is taking place at Mount Sinai Hospital in New York City.

Do you have pulmonary arterial hypertension? Do you have pulmonary arterial hypertension? Increasing physical activity is helpful for people with pulmonary arterial hypertension. Researchers are testing whether sending text messages is an effective way to encourage people with pulmonary arterial hypertension to be more physically active. You must be 18 years old to participate. The study is taking place in Nashville, Tennessee.
The Investigators propose a randomized trial of smart texts versus usual care for 6 months. The Investigators will randomize 100 PAH patients to the mHealth intervention or usual care. The Investigators will test the effect of a text-based mHealth intervention on HRQOL in PAH using the PAH-specific emPHasis-10 questionnaire. The Investigators will also test the effect of an mHealth intervention on exercise capacity, measured by a supervised home-based 6MWD test. Finally, the Investigators will examine the effect of the intervention on time to clinical worsening (composite of PAH therapy escalation, PAH hospitalization, and death) one year after randomization.

The goal of the study is to look at the relationship between how individuals with Sarcoidosis take the sarcoidosis medicines and how it affects the disease, to evaluate any factors that may make individuals not want to take the medicines, and to develop and refine ways to help support individuals with Sarcoidosis especially when it comes to the medicines.

Have you been taking medication to treat high blood pressure for at least 3 months? In this study, researchers explore whether a smartphone app can help people eat less salt and improve their blood pressure. Participants must be at least 18 years old, be taking medication to treat high blood pressure, and have a smartphone. The study is taking place in Ann Arbor, Michigan.

Are you scheduled for cardiac bypass surgery? Cardiac surgery is effective for improving the health of patients with cardiovascular disease, but many patients experience complications. In this clinical trial, researchers are collecting data to learn how different types of bypasses affect patients. You must be 50 to 70 years old to participate and be scheduled for elective cardiac surgery. The study is taking place in Aurora, Colorado.

Are you between the ages of 18 and 50 and diagnosed with Friedreich's ataxia? In this study, researchers are testing a new medication, gene therapy, to treat cardiomyopathy associated with Friedreich's ataxia, and you may be able to participate if you are not taking any corticosteroids or immunosuppressive medications to treat Friedreich's ataxia. This study is taking place in New York City, New York.