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Imagine having a digital carbon copy of yourself that physicians could use to predict long-term risks for disease, assess how your body may respond to treatment, and simulate surgeries in advance. A virtual twin may sound as far-fetched as robotic surgery and self-driving cars once did, but researchers are studying how to turn this vision into a...

Pairings like peanut butter and jelly or milk and cereal are iconic. But the concept of creating winning combinations is not limited to the kitchen; it is a fundamental principle driving the revolutionary field of synthetic biology, or synbio. “Synbio is a cutting-edge discipline at the intersection of biology and engineering, where scientists...

Researchers share insight about strategies being studied to support the cardiovascular health of people living with HIV When Tom Ortiz was diagnosed with HIV more than 30 years ago, he felt like he was handed a death sentence. “In the early days, if AIDS didn’t kill you a heart attack would,” said Ortiz, a community health worker in Ohio. “It was...

You may have heard sleep described as something of a magic pill for the body. With the right amount, timing, and quality, it can work wonders - strengthen the immune system, improve blood sugar, even decrease the risk of heart attacks and strokes. Sleep differences have been reported for some time in men and women, but it is not well known whether...

Inflammation can exacerbate risks for cardiovascular disease — and is informing new approaches for treatment Like a fire alarm sending signals to evacuate a smoky building, the immune system has internal guards to help the body sense and respond to danger. However, for people with risks for heart disease, these warning signals can have a negative...

Despite popularity of fish oil omega-3 supplements, big knowledge gaps remain Chances are, you or someone you know takes fish oil capsules with hopes of preventing heart disease - the leading cause of death. Made from omega-3 fatty acids, which the body cannot make on its own, they are among the most common type of dietary supplement used by U.S...

A new solution to an old problem makes breath analysis in real time possible The breath we exhale can tell us a lot about our respiratory and metabolic health – like whether we have asthma or if we might be developing kidney disease or need to better manage a case of COPD. But the breath is famously hard to study, especially in real time....

Sickle cell disease (SCD) is a group of painful and life-threatening genetic disorders that affect hemoglobin, the major protein that carries oxygen in red blood cells. It occurs in nearly 100,000 people in the United States and millions worldwide. The most common type is hemoglobin SS (HbSS), which affects about 65% of those with sickle cell...

The aorta, one of the “great arteries,” carries blood away from the heart to support circulation throughout the body. However, sometimes a tear in the lining of the aorta can occur, and while this is uncommon, it often requires immediate treatment. That’s why it’s important for people to be aware of common risk factors and symptoms. Sujata M...

Could next-generation gene editing mean a cure for cystic fibrosis (CF)? There's been a lot of advancement on the disease in the last decade, but there are still those living with the disease who get no relief from current treatments - especially those for whom health disparities already exist. Paul McCray, M.D., professor of pediatrics, and...