Blood Clotting Disorders Types

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Blood clotting disorders can either be inherited or acquired.

• “Inherited” means that your parents passed the gene for the disease on to you. Mutations, or changes in certain genes , can make your blood more likely to form clots. Some genetic changes are more common than others. The common genetic changes are not as likely to cause serous blood clots as the rarer genetic changes. 
• “Acquired” means that you weren’t born with the disease, but you developed it due to another disease or condition.

Just because you have a blood clotting disorder does not mean that you will develop blood clots. But it does increase your chance of having blood clots throughout your lifetime.

Common inherited blood clotting disorders include:

• Factor V Leiden mutation, which occurs in 5% of people of European descent
• Prothrombin G20210A mutation (also called factor II mutation), which occurs in 2% of the population

Rare inherited blood clotting disorders include:

• Deficiencies in blood clotting proteins called protein C, protein S, and antithrombin
• Hyperhomocysteinemia
• Sticky platelet syndrome

Examples of acquired blood clotting disorders include:

• Antiphospholipid syndrome (APS): This is the most common acquired clotting disorder. APS is an autoimmune condition where the body makes antibodies that mistakenly attack cell molecules called phospholipids. Higher levels of APS antibodies in the blood raise the risk of blood clots.
• Disseminated intravascular coagulation (DIC): This condition is caused by an infection (such as sepsis ) or an injury.