Stem Cell Allogeneic Transplantation

Current research in Stem Cell Transplantation (SCT) focuses on improving transplant outcome through immune manipulations using cell therapy and lymphocyte growth factors.

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John Barrett

Featured Publications

Inhibitors of ORAI1 Prevent Cytosolic Calcium-Associated Injury of Human Pancreatic Acinar Cells and Acute Pancreatitis in 3 Mouse Models.

Authors: Wen L, Voronina S, Javed MA, Awais M, Szatmary P, Latawiec D, Chvanov M, Collier D, Huang W, Barrett J, Begg M, Stauderman K, Roos J, Grigoryev S, Ramos S, Rogers E, Whitten J, Velicelebi G, Dunn M, Tepikin AV, Criddle DN, Sutton R
Gastroenterology 2015 Aug 01;149(2):481-92.e7
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Clinical comorbidity predictive measures in ex vivo T-cell-depleted allogeneic hematopoietic stem cell transplantation.

Authors: Le RQ, Tian X, Jain NA, Lu K, Ito S, Draper DA, Anandi P, Hourigan CS, Dunavin N, John Barrett A, Battiwalla M
Bone Marrow Transplant 2015 Aug 01;50(8):1138-40
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The role of stem cell transplantation for chronic myelogenous leukemia in the 21st century.

Authors: Barrett AJ, Ito S
Blood 2015 May 21;125(21):3230-3235
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Minor ABO Incompatibility Does Not Impact Nonrelapse Mortality in T Cell-Depleted Human Leukocyte Antigen-Matched Sibling Transplantation.

Authors: Chokshi P, Anandi P, Jain N, Dunavin N, Le RQ, Ito S, Barrett J, Battiwalla M
Biol Blood Marrow Transplant 2015 May 01;21(5):954-5
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CMV-specific T cells generated from naïve T cells recognize atypical epitopes and may be protective in vivo.

Authors: Hanley PJ, Melenhorst JJ, Nikiforow S, Scheinberg P, Blaney JW, Demmler-Harrison G, Cruz CR, Lam S, Krance RA, Leung KS, Martinez CA, Liu H, Douek DC, Heslop HE, Rooney CM, Shpall EJ, Barrett AJ, Rodgers JR, Bollard CM
Sci Transl Med 2015 Apr 29;7(285):285ra63
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Meet the Team

John Barrett

Austin Barrett, M.D.

Senior Investigator

Dr. John Barrett received his M.B. and B.S. degrees from the Medical College of St. Bartholomew’s Hospital, London in 1968, and his M.D. degree from University of London in 1975. From 1982 to 1988 he was Professor of Hematology and Head of the Department of Hematology at Charing Cross and Westminster Medical School, London, and from 1988 to 1993 he was Professor of Hematological Medicine at the Hammersmith Hospital, London. Dr. Barrett joined the NHLBI in 1993, as the chief of the Bone Marrow Stem Cell Allotransplantation Section of the Hematology Branch. He has received numerous honors for his contributions to hematology and stem cell transplantation including awards from the National Institutes of Health,  the National Health Service UK and the 2016 award from the American College of Physicans for science as it relates to medicine. Dr. Barrett was elected a Fellow of the Royal College of Physicians in 1998. He has authored over 350 original scientific articles, and nearly 150 reviews, editorials, and book chapters. He serves on numerous journal editorial boards and is the Editor in Chief for Cytotherapy. Dr. Barrett is a member of the British Society for Haematology, American Society of Hematology, American Society for Blood and Bone Marrow Transplantation (for which he served as President in 2010), and International Society for Cell Therapy, among other organizations.