Cardiac Energetics

As a serendipitous offshoot of their efforts in non-linear microscopy, Dr. Balaban and his colleagues discovered that they could visualize the composition of blood vessel walls without the need for dyes. They are using this method to study the early stages of atherosclerosis. Based on the evidence they have obtained, Dr. Balaban is testing the hypothesis that atherosclerotic lesion formation is dependent upon the extracellular matrix composition of the vascular wall.

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Balaban

Featured Publications

Mitochondrial DNA Segregation and Replication Restrict the Transmission of Detrimental Mutation

Authors: Chen Z, Wang ZH, Zhang G, Bleck CKE, Chung DJ, Madison GP, Lindberg E, Combs C, Balaban RS, Xu H.
J Cell Biol. 2020 Jul 06;219(7):e201905160
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Robust fluorescent labelling of micropipettes for use in fluorescence microscopy: application to the observation of a mosquito borne parasite infection

Authors: Balaban AE, Neuman K, Sinnis P, Balaban RS.
J Microsc. 2018 Jan 01;269(1):78-84
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The electrochemical transmission in I-Band segments of the mitochondrial reticulum.

Authors: Patel KD, Glancy B, Balaban RS
Biochim Biophys Acta 2016 Aug 01;1857(8):1284-9
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A Model-based approach for microvasculature structure distortion correction in two-photon fluorescence microscopy images.

Authors: Dao L, Glancy B, Lucotte B, Chang LC, Balaban RS, Hsu LY
J Microsc 2015 Nov 01;260(2):180-93
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Mitochondrial reticulum for cellular energy distribution in muscle.

Authors: Glancy B, Hartnell LM, Malide D, Yu ZX, Combs CA, Connelly PS, Subramaniam S, Balaban RS
Nature 2015 Jul 30;523(7562):617-20
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Meet the Team

Balaban

Robert Balaban, Ph.D.

Scientist Emeritus

Robert Balaban received his B.S. in biology and chemistry from the University of Miami in 1971 and his Ph.D. in physiology and pharmacology from Duke University in 1980. He was awarded a NATO fellowship to the Department of Biochemistry at the University of Oxford in 1981. In 1982, Dr. Balaban joined the NIH as a staff fellow in the NHLBI Laboratory of Kidney and Electrolyte Metabolism. He was named Chief of the newly formed Laboratory of Cardiac Energetics in 1988. Dr. Balaban served as trustee and president of the Society for Magnetic Resonance in Medicine from 1994 to 1995, of the International Society for Magnetic Resonance in Medicine from 1995 to 1996, and of the Society for Cardiovascular Magnetic Resonance from 1999 to 2001. He is a member of the American Physiological Society, the International Society for Magnetic Resonance in Medicine, the Society for Cardiovascular Magnetic Resonance, the American Society for Cell Biology, and the Biophysical Society.

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